MicroRNA Genes and Their Target 3′-Untranslated Regions Are Infrequently Somatically Mutated in Ovarian Cancers

MicroRNAs are key regulators of gene expression and have been shown to have altered expression in a variety of cancer types, including epithelial ovarian cancer. MiRNA function is most often achieved through binding to the 3′-untranslated region of the target protein coding gene. Mutation screening...

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Main Authors: Ryland, Georgina L., Bearfoot, Jennifer L., Doyle, Maria A., Boyle, Samantha E., Choong, David Y. H., Rowley, Simone M., Tothill, Richard W., Gorringe, Kylie L., Campbell, Ian G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334977/
https://ncbi.nlm.nih.gov/pubmed/22536442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035805
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