טוען...
The role of APP and BACE1 trafficking in APP processing and amyloid-β generation
Neuritic plaques in the brain are a major neuropathological hallmark of Alzheimer’s disease. They are formed by the deposition and aggregation of extracellular amyloid-β protein (Aβ). Aβ is derived from the sequential cleavage of amyloid-β precursor protein (APP) by β-secretase and γ-secretase. β-Si...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BioMed Central
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978418/ https://ncbi.nlm.nih.gov/pubmed/24103387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt211 |
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