Tumor-Suppressive Activity of Lunatic Fringe in Prostate through Differential Modulation of Notch Receptor Activation

Elevated Notch ligand and receptor expression has been associated with aggressive forms of prostate cancer, suggesting a role for Notch signaling in regulation of prostate tumor initiation and progression. Here, we report a critical role for Lunatic Fringe (Lfng), which encodes an O-fucosylpeptide 3...

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Bibliographic Details
Main Authors: Zhang, Shubing, Chung, Wen-cheng, Wu, Guanming, Egan, Sean E, Xu, Keli
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978396/
https://ncbi.nlm.nih.gov/pubmed/24709423
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