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Manic Fringe Promotes A Claudin-Low Breast Cancer Phenotype through Notch-Mediated PIK3CG Induction

Claudin-low breast cancer (CLBC) is a poor prognosis disease biologically characterized by stemness and mesenchymal features. These tumors disproportionately affect younger patients and women with African ancestry, causing significant morbidity and mortality, and no effective targeted therapy exists...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Zhang, Shubing, Chung, Wen-Cheng, Wu, Guanming, Egan, Sean E., Miele, Lucio, Xu, Keli
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433600/
https://ncbi.nlm.nih.gov/pubmed/25808869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3303
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