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Manic Fringe Promotes A Claudin-Low Breast Cancer Phenotype through Notch-Mediated PIK3CG Induction

Claudin-low breast cancer (CLBC) is a poor prognosis disease biologically characterized by stemness and mesenchymal features. These tumors disproportionately affect younger patients and women with African ancestry, causing significant morbidity and mortality, and no effective targeted therapy exists...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Zhang, Shubing, Chung, Wen-Cheng, Wu, Guanming, Egan, Sean E., Miele, Lucio, Xu, Keli
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433600/
https://ncbi.nlm.nih.gov/pubmed/25808869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3303
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