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Manic Fringe Promotes A Claudin-Low Breast Cancer Phenotype through Notch-Mediated PIK3CG Induction

Claudin-low breast cancer (CLBC) is a poor prognosis disease biologically characterized by stemness and mesenchymal features. These tumors disproportionately affect younger patients and women with African ancestry, causing significant morbidity and mortality, and no effective targeted therapy exists...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Zhang, Shubing, Chung, Wen-Cheng, Wu, Guanming, Egan, Sean E., Miele, Lucio, Xu, Keli
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433600/
https://ncbi.nlm.nih.gov/pubmed/25808869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3303
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