Delayed onset of paresis in rats with experimental intramedullary spinal cord gliosarcoma following intratumoral administration of the paclitaxel delivery system OncoGel: Laboratory investigation

OBJECT: Treatment options for anaplastic or malignant intramedullary spinal cord tumors (IMSCTs) remain limited. Paclitaxel has potent cytotoxicity against experimental intracranial gliomas and could be beneficial in the treatment of IMSCTs, but poor CNS penetration and significant toxicity limit it...

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Main Authors: Tyler, Betty M., Hdeib, Alia, Caplan, Justin, Legnani, Federico G., Fowers, Kirk D., Brem, Henry, Jallo, George, Pradilla, Gustavo
格式: Artigo
語言:Inglês
出版: 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978141/
https://ncbi.nlm.nih.gov/pubmed/22208429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2011.9.SPINE11435
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