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Improvement of HIV fusion inhibitor C34 efficacy by membrane anchoring and enhanced exposure
OBJECTIVES: The aim of the present work was to evaluate the interaction of two new HIV fusion inhibitors {HIVP3 [C34–polyethylene glycol (PEG)(4)–cholesterol] and HIVP4 [(C34–PEG(4))(2)–cholesterol]} with membrane model systems and human blood cells in order to clarify where and how the fusion inhib...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977611/ https://ncbi.nlm.nih.gov/pubmed/24464268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt529 |
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