Diastereoselective Synthesis of γ- and δ-Lactams from Imines and Sulfone-Substituted Anhydrides

[Image: see text] Sulfone-substituted γ- and δ-lactams have been prepared in a single step with high diastereoselectivity. Sulfonylglutaric anhydrides produce intermediates that readily decarboxylate to provide δ-lactams with high diastereoselectivity. Substituents at the 3- or 4-position of the glu...

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Главные авторы: Sorto, Nohemy A., Di Maso, Michael J., Muñoz, Manuel A., Dougherty, Ryan J., Fettinger, James C., Shaw, Jared T.
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2014
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977582/
https://ncbi.nlm.nih.gov/pubmed/24552208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo500050n
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