Directed elongation model for microtubule GTP hydrolysis.
We propose a role for GTP hydrolysis in microtubule assembly in which the GTPase reaction serves to stabilize tubulin subunits in the microtubule. The GTPase reaction in tubulin subunits containing GTP at microtubule ends is presumed to occur predominately in subunits at one of the interfaces betwee...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1985
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3858823/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.10.3267 |
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