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Hydrolysis-deficient mosaic microtubules as faithful mimics of the GTP cap

Abstract A critical feature of microtubules is their GTP cap, a stabilizing GTP-tubulin rich region at growing microtubule ends. Microtubules polymerized in the presence of GTP analogs or from GTP hydrolysis-deficient tubulin mutants have been used as GTP-cap mimics for structural and biochemical st...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Juan Estévez-Gallego, Thorsten B. Blum, Felix Ruhnow, María Gili, Silvia Speroni, Raquel García-Castellanos, Michel O. Steinmetz, Thomas Surrey
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2025-03-01
Rangatū:Nature Communications
Urunga tuihono:https://doi.org/10.1038/s41467-025-57555-6
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