Hydrolysis-deficient mosaic microtubules as faithful mimics of the GTP cap

Abstract A critical feature of microtubules is their GTP cap, a stabilizing GTP-tubulin rich region at growing microtubule ends. Microtubules polymerized in the presence of GTP analogs or from GTP hydrolysis-deficient tubulin mutants have been used as GTP-cap mimics for structural and biochemical st...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Juan Estévez-Gallego, Thorsten B. Blum, Felix Ruhnow, María Gili, Silvia Speroni, Raquel García-Castellanos, Michel O. Steinmetz, Thomas Surrey
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Nature Portfolio 2025-03-01
Cyfres:	Nature Communications
Mynediad Ar-lein:	https://doi.org/10.1038/s41467-025-57555-6
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!