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Role of GTP hydrolysis in microtubule treadmilling and assembly.

GTP hydrolysis accompanies addition of tubulin to microtubules. I find that hydrolysis is a requirement for the opposite-end assembly/disassembly of microtubules and consequent subunit treadmilling from one end to the other of the polymer. Neither GDP nor guanosine 5'-[beta, gamma-imido]triphos...

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Bibliografske podrobnosti
Glavni avtor: Margolis, R L
Format: Artigo
Jezik:Inglês
Izdano: 1981
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC319176/
https://ncbi.nlm.nih.gov/pubmed/6940174
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