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In vivo reprogramming of pancreatic acinar cells to three islet endocrine subtypes
Direct lineage conversion of adult cells is a promising approach for regenerative medicine. A major challenge of lineage conversion is to generate specific cell subtypes. The pancreatic islets contain three major hormone-secreting endocrine subtypes: insulin(+) β-cells, glucagon(+) α-cells, and soma...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977343/ https://ncbi.nlm.nih.gov/pubmed/24714494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01846 |
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