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Carrier Frequency of the c.525delT Mutation in the SGCG Gene and Estimated Prevalence of Limb Girdle Muscular Dystrophy Type 2C Among the Moroccan Population

Autosomal recessive limb-girdle muscular dystrophies (AR-LGMDs) are characterized by clinical and genetic heterogeneity. LGMD type 2C, or γ-sarcoglycanopathy, is the most frequent in North African populations as a result of the founder c.525delT mutation in the SGCG gene. Its epidemiology is poorly...

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Autors principals: El Kerch, Fatiha, Ratbi, Ilham, Sbiti, Aziza, Laarabi, Fatima-Zohra, Barkat, Amina, Sefiani, Abdelaziz
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977339/
https://ncbi.nlm.nih.gov/pubmed/24552312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/gtmb.2013.0326
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