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New Approaches Towards Recognition of Nucleic Acid Triple Helices

We show that groove recognition of nucleic acid triple helices can be achieved with aminosugars. Among these aminosugars, neomycin is the most effective aminoglycoside (groove binder) for stabilizing a DNA triple helix. It stabilizes both the T·A·T triplex and mixed-base DNA triplexes better than kn...

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Detalles Bibliográficos
Autor Principal: Arya, Dev P.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977315/
https://ncbi.nlm.nih.gov/pubmed/21073199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar100113q
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