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New Approaches Towards Recognition of Nucleic Acid Triple Helices

We show that groove recognition of nucleic acid triple helices can be achieved with aminosugars. Among these aminosugars, neomycin is the most effective aminoglycoside (groove binder) for stabilizing a DNA triple helix. It stabilizes both the T·A·T triplex and mixed-base DNA triplexes better than kn...

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Autor principal: Arya, Dev P.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977315/
https://ncbi.nlm.nih.gov/pubmed/21073199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar100113q
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