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New Approaches Towards Recognition of Nucleic Acid Triple Helices
We show that groove recognition of nucleic acid triple helices can be achieved with aminosugars. Among these aminosugars, neomycin is the most effective aminoglycoside (groove binder) for stabilizing a DNA triple helix. It stabilizes both the T·A·T triplex and mixed-base DNA triplexes better than kn...
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| Autor principal: | |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977315/ https://ncbi.nlm.nih.gov/pubmed/21073199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar100113q |
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