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Sequence-specific recognition of double helical nucleic acids by proteins.

The base pairs in double helical nucleic acids have been compared to see how they can be recognized by proteins. We conclude that a single hydrogen bond is inadequate for uniquely identifying any particular base pair, as this leads to numerous degeneracies. However, using two hydrogen bonds, fidelit...

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Detalhes bibliográficos
Main Authors: Seeman, N C, Rosenberg, J M, Rich, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1976
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC336007/
https://ncbi.nlm.nih.gov/pubmed/1062791
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