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Mapping protein conformational heterogeneity under pressure with site-directed spin labeling and double electron–electron resonance

The dominance of a single native state for most proteins under ambient conditions belies the functional importance of higher-energy conformational states (excited states), which often are too sparsely populated to allow spectroscopic investigation. Application of high hydrostatic pressure increases...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lerch, Michael T., Yang, Zhongyu, Brooks, Evan K., Hubbell, Wayne L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977274/
https://ncbi.nlm.nih.gov/pubmed/24707053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403179111
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