Genetic rearrangement of DNA induces knots with a unique topology: implications for the mechanism of synapsis and crossing-over.
We have determined the topological sign of the knots produced by a cycle of phage lambda integrative recombination. To insure that these knots reflect intrinsic features of the reaction mechanism, the substrate was constructed so that random interwrapping of segments of DNA played a minimal role in...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1985
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397727/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3159013/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.10.3124 |
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