Genetic rearrangement of DNA induces knots with a unique topology: implications for the mechanism of synapsis and crossing-over.
We have determined the topological sign of the knots produced by a cycle of phage lambda integrative recombination. To insure that these knots reflect intrinsic features of the reaction mechanism, the substrate was constructed so that random interwrapping of segments of DNA played a minimal role in...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1985
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397727/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3159013/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.10.3124 |
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