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Molecular Pathways: HER3 targeted therapy
The human epidermal receptor (HER) family of receptor tyrosine kinases, including EGFR, HER2, HER3 and HER4, transduce growth promoting signals in response to ligand-binding to their extra cellular domains. This family is deregulated in numerous cancers, with mutations in EGFR and HER2 often serving...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977203/ https://ncbi.nlm.nih.gov/pubmed/24520092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1549 |
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