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Targeting HER proteins in cancer therapy and the role of the non-target HER3

Members of the human epidermal growth factor receptor (HER) family have been of considerable interest in the cancer arena due to their potential to induce tumorigenesis when their signalling functions are deregulated. The constitutive activation of these proteins is seen in a number of different com...

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Autori principali: Hsieh, A C, Moasser, M M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360352/
https://ncbi.nlm.nih.gov/pubmed/17667926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603910
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