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Simplified and Efficient Quantification of Low-abundance Proteins at Very High Multiplex via Targeted Mass Spectrometry

Liquid chromatography–multiple reaction monitoring mass spectrometry (LC-MRM-MS) of plasma that has been depleted of abundant proteins and fractionated at the peptide level into six to eight fractions is a proven method for quantifying proteins present at low nanogram-per-milliliter levels. A drawba...

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Bibliografski detalji
Glavni autori: Burgess, Michael W., Keshishian, Hasmik, Mani, D. R., Gillette, Michael A., Carr, Steven A.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977191/
https://ncbi.nlm.nih.gov/pubmed/24522978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.034660
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