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Cell death and the mitochondria: therapeutic targeting of the BCL-2 family-driven pathway

The principal biological role of mitochondria is to supply energy to cells; although intriguingly, evolution has bestowed another essential function upon these cellular organelles: under physiological stress, mitochondria become the cornerstone of apoptotic cell death. Specifically, mitochondrial ou...

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Bibliografiske detaljer
Main Authors: Roy, M J, Vom, A, Czabotar, P E, Lessene, G
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976616/
https://ncbi.nlm.nih.gov/pubmed/24117105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12431
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