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The cAMP-responsive element binding protein (CREB) regulates the expression of acid ceramidase (ASAH1) in H295R human adrenocortical cells

Acid ceramidase (encoded by ASAH1) is a lipid hydrolase that catalyzes the conversion of ceramide (cer) into sphingosine (SPH) and a free fatty acid. Adrenocortical steroidogenesis is regulated by the trophic peptide hormone adrenocorticotropin (ACTH), which induces the expression of steroidogenic g...

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Autori principali: Lucki, Natasha, Sewer, Marion B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976422/
https://ncbi.nlm.nih.gov/pubmed/19298866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2009.03.005
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