Acid Ceramidase (ASAH1) Represses Steroidogenic Factor 1-Dependent Gene Transcription in H295R Human Adrenocortical Cells by Binding to the Receptor

Adrenocorticotropin (ACTH) signaling increases glucocorticoid production by promoting the interaction of transcription factors and coactivator proteins with the promoter of steroidogenic genes. The nuclear receptor steroidogenic factor 1 (SF-1) is essential for steroidogenic gene transcription. Sphi...

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Main Authors: Lucki, Natasha C., Li, Donghui, Bandyopadhyay, Sibali, Wang, Elaine, Merrill, Alfred H., Sewer, Marion B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486137/
https://ncbi.nlm.nih.gov/pubmed/22927646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00378-12
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