Long-Term Weight-Loss in Gastric Bypass Patients Carrying Melanocortin 4 Receptor Variants

BACKGROUND: The melanocortin 4 receptor (MC4R) critically regulates feeding and satiety. Rare variants in MC4R are predominantly found in obese individuals. Though some rare variants in MC4R discovered in patients have defects in localization, ligand binding and signaling to cAMP, many have no recog...

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Main Authors: Moore, Bryn S., Mirshahi, Uyenlinh L., Yost, Evan A., Stepanchick, Ann N., Bedrin, Michael D., Styer, Amanda M., Jackson, Kathryn K., Still, Christopher D., Breitwieser, Gerda E., Gerhard, Glenn S., Carey, David J., Mirshahi, Tooraj
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976318/
https://ncbi.nlm.nih.gov/pubmed/24705671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093629
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