Long-term weight-loss in gastric bypass patients carrying melanocortin 4 receptor variants.

The melanocortin 4 receptor (MC4R) critically regulates feeding and satiety. Rare variants in MC4R are predominantly found in obese individuals. Though some rare variants in MC4R discovered in patients have defects in localization, ligand binding and signaling to cAMP, many have no recognized defect...

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Bibliografische gegevens
Hoofdauteurs: Bryn S Moore, Uyenlinh L Mirshahi, Evan A Yost, Ann N Stepanchick, Michael D Bedrin, Amanda M Styer, Kathryn K Jackson, Christopher D Still, Gerda E Breitwieser, Glenn S Gerhard, David J Carey, Tooraj Mirshahi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2014-01-01
Reeks:PLoS ONE
Online toegang:http://europepmc.org/articles/PMC3976318?pdf=render
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