Long-Term Weight-Loss in Gastric Bypass Patients Carrying Melanocortin 4 Receptor Variants

BACKGROUND: The melanocortin 4 receptor (MC4R) critically regulates feeding and satiety. Rare variants in MC4R are predominantly found in obese individuals. Though some rare variants in MC4R discovered in patients have defects in localization, ligand binding and signaling to cAMP, many have no recog...

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Αποθηκεύτηκε σε:
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Κύριοι συγγραφείς: Moore, Bryn S., Mirshahi, Uyenlinh L., Yost, Evan A., Stepanchick, Ann N., Bedrin, Michael D., Styer, Amanda M., Jackson, Kathryn K., Still, Christopher D., Breitwieser, Gerda E., Gerhard, Glenn S., Carey, David J., Mirshahi, Tooraj
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2014
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976318/
https://ncbi.nlm.nih.gov/pubmed/24705671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093629
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