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Pancreatic Alpha-Cell Dysfunction Contributes to the Disruption of Glucose Homeostasis and Compensatory Insulin Hypersecretion in Glucocorticoid-Treated Rats

Glucocorticoid (GC)-based therapies can cause insulin resistance (IR), glucose intolerance, hyperglycemia and, occasionally, overt diabetes. Understanding the mechanisms behind these metabolic disorders could improve the management of glucose homeostasis in patients undergoing GC treatment. For this...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rafacho, Alex, Gonçalves-Neto, Luiz M., Santos-Silva, Junia C., Alonso-Magdalena, Paloma, Merino, Beatriz, Taboga, Sebastião R., Carneiro, Everardo M., Boschero, Antonio C., Nadal, Angel, Quesada, Ivan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976288/
https://ncbi.nlm.nih.gov/pubmed/24705399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093531
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