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Pancreatic alpha-cells from female mice undergo morphofunctional changes during compensatory adaptations of the endocrine pancreas to diet-induced obesity

Obesity is frequently associated with insulin resistance. To compensate for this situation and maintain normoglycaemia, pancreatic beta-cells undergo several morphofunctional adaptations, which result in insulin hypersecretion and hyperinsulinaemia. However, no information exists about pancreatic al...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Merino, Beatriz, Alonso-Magdalena, Paloma, Lluesma, Mónica, Ñeco, Patricia, Gonzalez, Alejandro, Marroquí, Laura, García-Arévalo, Marta, Nadal, Angel, Quesada, Ivan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650619/
https://ncbi.nlm.nih.gov/pubmed/26108563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11622
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