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IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T-cells Abortively Infected with HIV

The progressive depletion of quiescent “bystander” CD4 T-cells, which are non-permissive to HIV infection, is a principal driver of the acquired immunodeficiency syndrome (AIDS). These cells undergo abortive infection characterized by the cytosolic accumulation of incomplete HIV reverse transcripts....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Monroe, Kathryn M., Yang, Zhiyuan, Johnson, Jeffrey R., Geng, Xin, Doitsh, Gilad, Krogan, Nevan J., Greene, Warner C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976200/
https://ncbi.nlm.nih.gov/pubmed/24356113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1243640
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