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Efficient delivery of lentiviral vectors into resting human CD4 T cells

Resting human CD4 T cells are highly resistant to transfection or infection with lentiviral vectors derived from the human immunodeficiency virus (HIV LV). We now describe a flexible and efficient approach that permits effective genetic manipulation of these cells while preserving their naturally qu...

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Detalhes bibliográficos
Main Authors: Geng, Xin, Doitsh, Gilad, Yang, Zhiyuan, Galloway, Nicole LK, Greene, Warner C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006095/
https://ncbi.nlm.nih.gov/pubmed/24572792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2014.5
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