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Ponatinib enhances anticancer drug sensitivity in MRP7-overexpressing cells

The presence of acquired multidrug resistance (MDR) is one of the primary impediments to the success of chemotherapy. MDR is often a result of overexpression of ATP-binding cassette (ABC) transporters, which are involved in the extrusion of therapeutic drugs. Recently, it was shown that several ABC...

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Hlavní autoři: SUN, YUE-LI, KUMAR, PRIYANK, SODANI, KAMLESH, PATEL, ATISH, PAN, YIHANG, BAER, MARIA R., CHEN, ZHE-SHENG, JIANG, WEN-QI
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975990/
https://ncbi.nlm.nih.gov/pubmed/24481648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2014.3002
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