Threonine 57 is required for the post-translational activation of Escherichia coli aspartate α-decarboxylase

Aspartate α-decarboxylase is a pyruvoyl-dependent decarboxylase required for the production of β-alanine in the bacterial pantothenate (vitamin B(5)) biosynthesis pathway. The pyruvoyl group is formed via the intramolecular rearrangement of a serine residue to generate a backbone ester intermediate...

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Autors principals: Webb, Michael E., Yorke, Briony A., Kershaw, Tom, Lovelock, Sarah, Lobley, Carina M. C., Kilkenny, Mairi L., Smith, Alison G., Blundell, Tom L., Pearson, Arwen R., Abell, Chris
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2014
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975893/
https://ncbi.nlm.nih.gov/pubmed/24699660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1399004713034275
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