Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis

Poly (ADP-ribose) polymerase 1 (PARP-1) is a constitutive enzyme, the major isoform of PARP family, which is involved in the regulation of DNA repair, cell death, metabolism, and inflammatory responses. Pharmacological inhibitors of PARP provide significant therapeutic benefits in various preclinica...

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Bibliografiske detaljer
Main Authors:	Mukhopadhyay, Partha, Rajesh, Mohanraj, Cao, Zongxian, Horváth, Béla, Park, Ogyi, Wang, Hua, Erdelyi, Katalin, Holovac, Eileen, Wang, Yuping, Liaudet, Lucas, Hamdaoui, Nabila, Lafdil, Fouad, Haskó, György, Szabo, Csaba, Boulares, A. Hamid, Gao, Bin, Pacher, Pal
Format:	Artigo
Sprog:	Inglês
Udgivet:	2014
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3975736/ https://ncbi.nlm.nih.gov/pubmed/24089324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26763
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Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis

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