Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide

BACKGROUND: Chemoresistance of glioblastoma multiforme (GBM) has been attributed to the presence within the tumor of cancer stem cells (GSCs). The standard therapy for GBM consists of surgery followed by radiotherapy and the chemotherapeutic agent temozolomide (TMZ). However, TMZ efficacy is limited...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tentori, Lucio, Ricci-Vitiani, Lucia, Muzi, Alessia, Ciccarone, Fabio, Pelacchi, Federica, Calabrese, Roberta, Runci, Daniele, Pallini, Roberto, Caiafa, Paola, Graziani, Grazia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975727/
https://ncbi.nlm.nih.gov/pubmed/24593254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-151
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados