Lysosomotropic agents selectively potentiate thrombin-induced acid hydrolase secretion from platelets.
Thrombin induces partial secretion (up to 60%) of beta-N-acetyl-D-hexosaminidase (EC 3.2.1.52) from untreated platelets. Preincubation of platelets with 10 mM NH4Cl for up to 2 hr resulted in a time-dependent and marked stimulation of thrombin-induced secretion of both this enzyme and other acid gly...
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1985
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397560/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3157989/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.8.2374 |
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