Lysosomotropic agents selectively potentiate thrombin-induced acid hydrolase secretion from platelets.

Thrombin induces partial secretion (up to 60%) of beta-N-acetyl-D-hexosaminidase (EC 3.2.1.52) from untreated platelets. Preincubation of platelets with 10 mM NH4Cl for up to 2 hr resulted in a time-dependent and marked stimulation of thrombin-induced secretion of both this enzyme and other acid gly...

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Bibliografske podrobnosti
Main Authors: Van Oost, B A, Smith, J B, Holmsen, H, Vladutiu, G D
Format: Artigo
Jezik:Inglês
Izdano: 1985
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC397560/
https://ncbi.nlm.nih.gov/pubmed/3157989
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