12-O-Tetradecanoylphorbol-13-Acetate Induces Keratin 8 Phosphorylation and Reorganization via Expression of Transglutaminase-2

The stiffness of cancer cells is attributable to intermediate filaments such as keratin. Perinuclear reorganization via phosphorylation of specific serine residue in keratin is implicated in the deformability of metastatic cancer cells including the human pancreatic carcinoma cell line (PANC-1). 12-...

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Bibliografiske detaljer
Main Authors: Lee, Eun Ji, Park, Mi Kyung, Kim, Hyun Ji, Kang, June Hee, Kim, You Ri, Kang, Gyeoung Jin, Byun, Hyun Jung, Lee, Chang Hoon
Format: Artigo
Sprog:Inglês
Udgivet: The Korean Society of Applied Pharmacology 2014
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975474/
https://ncbi.nlm.nih.gov/pubmed/24753817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2014.007
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