12-O-Tetradecanoylphorbol-13-Acetate Induces Keratin 8 Phosphorylation and Reorganization via Expression of Transglutaminase-2

The stiffness of cancer cells is attributable to intermediate filaments such as keratin. Perinuclear reorganization via phosphorylation of specific serine residue in keratin is implicated in the deformability of metastatic cancer cells including the human pancreatic carcinoma cell line (PANC-1). 12-...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, Eun Ji, Park, Mi Kyung, Kim, Hyun Ji, Kang, June Hee, Kim, You Ri, Kang, Gyeoung Jin, Byun, Hyun Jung, Lee, Chang Hoon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Korean Society of Applied Pharmacology 2014
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975474/
https://ncbi.nlm.nih.gov/pubmed/24753817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2014.007
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