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Anaphylaxis caused by repetitive doses of a GITR agonist monoclonal antibody in mice

Immunotherapy for cancer using antibodies to enhance T-cell function has been successful in recent clinical trials. Many molecules that improve activation and effector function of T cells have been investigated as potential new targets for immunomodulatory antibodies, including the tumor necrosis fa...

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Bibliografische gegevens
Hoofdauteurs: Murphy, Judith T., Burey, Andre P., Beebe, Amy M., Gu, Danling, Presta, Leonard G., Merghoub, Taha, Wolchok, Jedd D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975257/
https://ncbi.nlm.nih.gov/pubmed/24558202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-12-544742
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