A High-throughput Screening Assay using Krabbe Disease Patient Cells

Globoid-cell leukodystrophy (GLD) or Krabbe disease is a lysosomal disease caused by β-galactocerebrosidase (GALC) deficiency resulting in a rapidly progressive neurodegenerative disorder. Unfortunately, the only available treatment is hematopoietic bone marrow transplantation, which prevents its fu...

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Bibliografiset tiedot
Päätekijät: Ribbens, Jameson, Whiteley, Grace, Furuya, Hirokazu, Southall, Noel, Hu, Xin, Marugan, Juan, Ferrer, Marc, Maegawa, Gustavo H.B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975245/
https://ncbi.nlm.nih.gov/pubmed/23138179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2012.10.034
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