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A High-throughput Screening Assay using Krabbe Disease Patient Cells
Globoid-cell leukodystrophy (GLD) or Krabbe disease is a lysosomal disease caused by β-galactocerebrosidase (GALC) deficiency resulting in a rapidly progressive neurodegenerative disorder. Unfortunately, the only available treatment is hematopoietic bone marrow transplantation, which prevents its fu...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3975245/ https://ncbi.nlm.nih.gov/pubmed/23138179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2012.10.034 |
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