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Contributions of epithelial-mesenchymal transition and cancer stem cells to the development of castration resistance of prostate cancer

An important clinical challenge in prostate cancer therapy is the inevitable transition from androgen-sensitive to castration-resistant and metastatic prostate cancer. Albeit the androgen receptor (AR) signaling axis has been targeted, the biological mechanism underlying the lethal event of androgen...

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Detalhes bibliográficos
Main Authors: Li, Ping, Yang, Ru, Gao, Wei-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975176/
https://ncbi.nlm.nih.gov/pubmed/24618337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-55
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