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Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer
In colon cancer, mutation of the Wnt repressor Adenomatous polyposis coli (APC) leads to a state of aberrant and unrestricted “high-activity” signaling. However, relevance of high Wnt tone in non-genetic human disease is unknown. Here we demonstrate that distinct Wnt activity functional states deter...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3975168/ https://ncbi.nlm.nih.gov/pubmed/24609463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3676 |
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