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Restless Legs Syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon
Genome-wide association studies (GWAS) identified the MEIS1 locus for Restless Legs Syndrome (RLS), but causal single nucleotide polymorphisms (SNPs) and their functional relevance remain unknown. This locus contains a large number of highly conserved noncoding regions (HCNRs) potentially functionin...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3975059/ https://ncbi.nlm.nih.gov/pubmed/24642863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.166751.113 |
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