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The Efficacy of Raf Kinase Recruitment to the GTPase H-ras Depends on H-ras Membrane Conformer-specific Nanoclustering

Solution structures and biochemical data have provided a wealth of mechanistic insight into Ras GTPases. However, information on how much the membrane organization of these lipid-modified proteins impacts on their signaling is still scarce. Ras proteins are organized into membrane nanoclusters, whic...

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Detalhes bibliográficos
Main Authors: Guzmán, Camilo, Šolman, Maja, Ligabue, Alessio, Blaževitš, Olga, Andrade, Débora M., Reymond, Luc, Eggeling, Christian, Abankwa, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975003/
https://ncbi.nlm.nih.gov/pubmed/24569991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537001
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