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The Efficacy of Raf Kinase Recruitment to the GTPase H-ras Depends on H-ras Membrane Conformer-specific Nanoclustering

Solution structures and biochemical data have provided a wealth of mechanistic insight into Ras GTPases. However, information on how much the membrane organization of these lipid-modified proteins impacts on their signaling is still scarce. Ras proteins are organized into membrane nanoclusters, whic...

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書誌詳細
主要な著者: Guzmán, Camilo, Šolman, Maja, Ligabue, Alessio, Blaževitš, Olga, Andrade, Débora M., Reymond, Luc, Eggeling, Christian, Abankwa, Daniel
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975003/
https://ncbi.nlm.nih.gov/pubmed/24569991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537001
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