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Proteolysis of Apolipoprotein A-I by Secretory Phospholipase A(2): A NEW LINK BETWEEN INFLAMMATION AND ATHEROSCLEROSIS
In the acute phase of the inflammatory response, secretory phospholipase A(2) (sPLA(2)) reaches its maximum levels in plasma, where it is mostly associated with high density lipoproteins (HDL). Overexpression of human sPLA(2) in transgenic mice reduces both HDL cholesterol and apolipoprotein A-I (ap...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3974973/ https://ncbi.nlm.nih.gov/pubmed/24523407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.525717 |
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