Structural Basis for PI(4)P-Specific Membrane Recruitment of the Legionella pneumophila Effector DrrA/SidM

Recruitment of the Legionella pneumophila effector DrrA to the Legionella-containing vacuole, where it activates and AMPylates Rab1, is mediated by a P4M domain that binds phosphatidylinositol 4-phosphate [PI(4)P] with high affinity and specificity. Despite the importance of PI(4)P in Golgi traffick...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Del Campo, Claudia M., Mishra, Ashwini K., Wang, Yu-Hsiu, Roy, Craig R., Janmey, Paul A., Lambright, David G.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974903/
https://ncbi.nlm.nih.gov/pubmed/24530282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.12.018
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker