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Structural insights into the dual nucleotide exchange and GDI displacement activity of SidM/DrrA

GDP-bound prenylated Rabs, sequestered by GDI (GDP dissociation inhibitor) in the cytosol, are delivered to destined sub-cellular compartment and subsequently activated by GEFs (guanine nucleotide exchange factors) catalysing GDP-to-GTP exchange. The dissociation of GDI from Rabs is believed to requ...

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Detalhes bibliográficos
Main Authors: Suh, Hye-Young, Lee, Dong-Won, Lee, Kwang-Hoon, Ku, Bonsu, Choi, Sung-Jin, Woo, Jae-Sung, Kim, Yeon-Gil, Oh, Byung-Ha
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824451/
https://ncbi.nlm.nih.gov/pubmed/19942850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.347
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