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Structural insights into the dual nucleotide exchange and GDI displacement activity of SidM/DrrA
GDP-bound prenylated Rabs, sequestered by GDI (GDP dissociation inhibitor) in the cytosol, are delivered to destined sub-cellular compartment and subsequently activated by GEFs (guanine nucleotide exchange factors) catalysing GDP-to-GTP exchange. The dissociation of GDI from Rabs is believed to requ...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824451/ https://ncbi.nlm.nih.gov/pubmed/19942850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.347 |
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